Efficient coupling of 2-halopyrimidines to 2,2′-bipyrimidines was written by Nasielski, J.;Standaert, A.;Nasielski-Hinkens, R.. And the article was included in Synthetic Communications in 1991.Recommanded Product: 2-Bromo-4,6-dimethylpyrimidine This article mentions the following:
Pyrimidines I (R = H, Me, Ph; R1 = Br, Cl) have been dimerized to the corresponding 2,2′-bipyrimidines in good yields by Tiecco’s method using NiCl2, PPh3 and Zn in DMF. In the experiment, the researchers used many compounds, for example, 2-Bromo-4,6-dimethylpyrimidine (cas: 16879-39-3Recommanded Product: 2-Bromo-4,6-dimethylpyrimidine).
2-Bromo-4,6-dimethylpyrimidine (cas: 16879-39-3) belongs to pyrimidine derivatives. The pyrimidine derivatives can easily interact with enzymes, genetic materials, and bio components within the cell. Drugs having the pyrimidine motif have manifested to exhibit gratifying biological activity like anticancer, antiviral, anti-inflammatory, antibacterial, and antihypertensive activities.Recommanded Product: 2-Bromo-4,6-dimethylpyrimidine
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia