Application of 3993-78-0, Catalysts allow a reaction to proceed via a pathway that has a lower activation energy than the uncatalyzed reaction. 3993-78-0, Name is 2-Amino-4-chloropyrimidine, SMILES is C1=CN=C(N=C1Cl)N, belongs to pyrimidines compound. In a article, author is Bhadraiah, Umesha K., introduce new discover of the category.
Thiazolo-Pyrimidine Analogues: Synthesis, Characterization and Docking Studies Guided Antimicrobial Activities
In the current stud. bicyclic 117-methy1-3.5-dipheny1-5H-thiazolo(3.2-alpha)pyrimidine-6-hanone (4a -I) derivatil es have been designed and conveniently synthesized by one -pot three component method vier cyclocondensation of substituted 4-phenylthiazole-2-amine (1a -c). acetylacetone (2) and arious aromatic aldehydes (3a -d) in the presence of p -toluene sulfonic acid (PTSA) under acetonitrile solvent medium. The synthesized compounds (4a -I) ha e been characterized by spectral analysis and subjected to docking study against protein DNA gyrase (PD13 (`ode: I KZN). and also. the compounds ere screened for their in vitro antimicrobial actin ities. The bioassay of the synthesized compounds ens isioned that the compound 4k emerged as a broad-spectrum antibacterial agent. and 41 emerged as a good antifungal agent compared to standard drug.
Application of 3993-78-0, Each elementary reaction can be described in terms of its molecularity, the number of molecules that collide in that step. The slowest step in a reaction mechanism is the rate-determining step.you can also check out more blogs about 3993-78-0.
Reference:
Pyrimidine | C4H4N2 – PubChem,
,Pyrimidine – Wikipedia