Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, Quality Control of 6-Chloro-3-methylpyrimidine-2,4(1H,3H)-dione, 4318-56-3, Name is 6-Chloro-3-methylpyrimidine-2,4(1H,3H)-dione, SMILES is O=C1N(C)C(C=C(Cl)N1)=O, belongs to pyrimidines compound. In a document, author is Singh, Ankita, introduce the new discover.
Synthesis, Self-Assembly, and Biological Activities of Pyrimidine-Based Cationic Amphiphiles
Pyrimidine-based cationic amphiphiles (PCAms), i.e., di-trifluoroacetic acid salts of N1-[1′-(1 ”,3 ”-diglycinatoxypropane- 2 ”-yl ) – 1′, 2′,3′-triazole-4′-yl] methyl-N3- alkylpyrimidines have been synthesized utilizing naturally occurring biocompatible precursors, like glycerol, glycine, and uracil/ thymine in good yields. Synthesized PCAms consist of a hydrophilic head group comprising TFA salt of glyceryl 1,3-diglycinate and hydrophobic tail comprising of C-7 and C-12 N3-alkylated uracil or thymine conjugated via a 4-methylene-1,2,3-triazolyl linker. The physicochemical properties of all PCAms, such as critical aggregation concentration, hydrodynamic diameter, shape, and zeta potential (surface charge) were analyzed. These PCAms were also evaluated for their anti-proliferative and anti-tubercular activities. One of the synthesized PCAm exhibited 4- to 75-fold more activity than first-line anti-tubercular drugs streptomycin and isoniazid, respectively, against the multidrug resistant clinical isolate 591 of Mycobacterium tuberculosis.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 4318-56-3 is helpful to your research. Quality Control of 6-Chloro-3-methylpyrimidine-2,4(1H,3H)-dione.
Reference:
Pyrimidine | C4H4N2 – PubChem,
,Pyrimidine – Wikipedia