In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 14080-23-0, name is 2-Cyanopyrimidine, the common compound, a new synthetic route is introduced below. Safety of 2-Cyanopyrimidine
a) 2-Aminomethyl-pyrimidine 66.2 g (0.63 mole) of 2-cyano-pyrimidine (Liebigs Ann. Chem. 1981, 333) in 1.9 1 of ethanol are hydrogenated in the presence of 130 ml of liquid ammonia and 5 g of Pd-C (5% Pd) at 20 C. and 5-10 bar of hydrogen. The catalyst is filtered off, the filtrate is concentrated and the residue is distilled. Yield: 48.8 g (71% of theory) Boiling point: 82 C./4 mbar
The synthetic route of 14080-23-0 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Bayer Aktiengesellschaft; US5312823; (1994); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia