New downstream synthetic route of 20781-06-0

According to the analysis of related databases, 20781-06-0, the application of this compound in the production field has become more and more popular.

Reference of 20781-06-0, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 20781-06-0, name is 2,4-Diaminopyrimidine-5-carboxaldehyde. This compound has unique chemical properties. The synthetic route is as follows.

1mmol 2,4-diamino-5-pyrimidinecarbaldehyde with1.1mmol benzoyl hydrazide is dissolved in 25ml ethanol solvent,Add 0.15 mmol of trifluoroacetic acid,Heat and stir the reaction for 6-8h,TLC monitors the progress of the reaction,Add 50ml of water after the reaction is completed.Stirring solids precipitated,Filtering,Drying gave a yellow solid.Yield 79%, m.p. 250-252 C;

According to the analysis of related databases, 20781-06-0, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Central China Normal University; He Hongwu; Zhou Yuan; (70 pag.)CN109503496; (2019); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia