New downstream synthetic route of 29939-37-5

Statistics shows that 29939-37-5 is playing an increasingly important role. we look forward to future research findings about 4-Hydroxy-6-hydrazinylpyrimidine.

Application of 29939-37-5, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.29939-37-5, name is 4-Hydroxy-6-hydrazinylpyrimidine, molecular formula is C4H6N4O, molecular weight is 126.12, as common compound, the synthetic route is as follows.

A mixture comprising 5.0 g (39.6 mmol) 6-hydrazinopyrimidin-4-ol/6-hydrazinopyrimidin-4(1H)-one (CAS-No: 29939-37-5), 5.12 g pentan-3-one and 80.8 ml ethanol was heated under reflux for 2 hours. After cooling to 3 C, the precipitated solid was filtered off and washed with diethyl ether to give 5.82 g (72%) of the title compound.

Statistics shows that 29939-37-5 is playing an increasingly important role. we look forward to future research findings about 4-Hydroxy-6-hydrazinylpyrimidine.

Reference:
Patent; BAYER PHARMA AKTIENGESELLSCHAFT; KLAR, Ulrich; WORTMANN, Lars; KETTSCHAU, Georg; PUeHLER, Florian; LIENAU, Philip; PETERSEN, Kirstin; HAeGEBARTH, Andrea; SUeLZLE, Detlev; WO2014/44691; (2014); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia