Adding a certain compound to certain chemical reactions, such as: 52854-14-5, 4-Chloro-6-methoxy-5-nitropyrimidine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Recommanded Product: 4-Chloro-6-methoxy-5-nitropyrimidine, blongs to pyrimidines compound. Recommanded Product: 4-Chloro-6-methoxy-5-nitropyrimidine
b) 4-Methoxypyrimidin-5-amine 10% Palladium on carbon (1.10 g) was added to a solution of 4-chloro-6-methoxy-5-nitropyrimidine (Preparation 25a, 1.97 g, 10.4 mmol) in ethanol (80 mL) and the reaction mixture was stirred at ambient temperature overnight under a hydrogen atmosphere at a pressure of 2 bars. The mixture was then filtered through Celite and the filter cake was washed with ethanol. The combined filtrate and washings were concentrated to give the title compound (1.30 g, 100%) as a solid. LRMS (m/z): 126 (M+1)+. 1H NMR delta (300 MHz, DMSO-d6): 4.11 (s, 3H), 7.91 (s, 1 H), 8.59 (s, 1 H).
The synthetic route of 52854-14-5 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Almirall, S.A.; EP2527344; (2012); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia