Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 36847-10-6, name is 4,6-Dibromopyrimidine. This compound has unique chemical properties. The synthetic route is as follows. name: 4,6-Dibromopyrimidine
35.7g in a dry 2L three-necked flask 4.6-dibromopyrimidine and 27.9 g 3-aminobiphenyl, Then dry and degassed 800 mL of toluene was added as a solvent. Add 43.2g of sodium tert-butoxide, 0.67g catalyst palladium acetate (2% mol) and 3.7g Ligand 1,1′-binaphthyl-2,2′-bisdiphenylphosphine (BINAP, 4% mol). The temperature was raised to 110C and the reaction ended overnight. Cool to room temperature, add activated carbon adsorption, suction filtration, remove solvent, Recrystallization from toluene and ethanol, 33.3 g of intermediate K was obtained (yield 68%).
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Reference:
Patent; Nanjing Gao Guang Semiconductor Materials Co., Ltd.; Jin Zhenyu; Qian Chao; Gao Penghui; Wang Xiaowei; (62 pag.)CN107686484; (2018); A;,
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