Adding a certain compound to certain chemical reactions, such as: 4869-46-9, 1,3-Dimethyluracil-5-carboxaldehyde, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Formula: C7H8N2O3, blongs to pyrimidines compound. Formula: C7H8N2O3
General procedure: A solution of sodium acetate trihydrate (0.41 g, 3 mmol) and NH2OH*HCl (0.37 g, 2.25 mmola) in H2O (3 mL) was added to a suspension of uracil 3 (0.34 g, 2 mmol) in EtOH (5 mL) while stirring at room temperature. After a few minutes a white solid started to precipitate and the stirring was continued for 24 h. A progress of the reaction was monitored by TLC (EtOAc : n-hexane, 2:1). The solid consisting of a mixture of two isomeric oximes was isolated in yield of 93% (0.34 g). The E/Z isomers were separated on silica gel column using MeOH : CHCl3 (5 :95, v/v) as an eluent. When the time of synthesis was extended to 48 h Z-isomer was obtained exclusively.
The synthetic route of 4869-46-9 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Jakubiec, Dominika; Przypis, ?ukasz; Suwi?ski, Jerzy W.; Walczak, Krzysztof Z.; Arkivoc; vol. 2017; 2; (2016); p. 149 – 161;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia