5750-76-5, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 5750-76-5, name is 2,4,5-Trichloropyrimidine. This compound has unique chemical properties. The synthetic route is as follows.
(E)-4-(2-butoxyvinyl)-2,5-dichloropyrimidine was obtained as follows: Triethylamine (19.4 ml, 139 mmol), 1-(vinyloxy)butane (18.0 ml, 139 mmol) and palladium(II) acetate (2.08 g, 9.30 mmol) were added to a stirred solution of 2,4,5-trichloropyrimidine (15 ml, 132 mmol) in polyethylene glycol 400 (150 ml). The solution was heated at 80 C. for 2 h. After cooling to 0 C., diethylether was added, the organic layer was separated and washed with brine, dried on MgSO4, filtered and evaporated to afford an orange oil. This oil was dissolved in 300 mL of a petroleum ether/AcOEt mixture (85:15), 40 g of silica was added and this suspension was filtered. The filtrate was evaporated to afford (E)-4-(2-butoxyvinyl)-2,5-dichloropyrimidine (18.0 g, 54%) as an orange oil; NMR spectrum: (CDCl3) 0.97 (t, 3H), 1.41-1.50 (m, 2H), 1.70-1.78 (m, 2H), 4.03 (t, 2H), 6.09 (d, 1H), 8.07 (d, 1H), 8.33 (s, 1H).
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 5750-76-5, 2,4,5-Trichloropyrimidine.
Reference:
Patent; ASTRAZENECA AB; US2010/105655; (2010); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia