Reference of 1004-39-3, Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 1004-39-3, name is 4,6-Diaminopyrimidine-2-thiol. A new synthetic method of this compound is introduced below.
To a suspension of commercially available 4,6-diaminopyrimidine-2-thiol (5g, 35mmol) in methanol (7OmL) is added IN sodium hydroxide (35mL). The resulting solution is stirred for Ih at rt then evaporated to give a tan solid.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,1004-39-3, 4,6-Diaminopyrimidine-2-thiol, and friends who are interested can also refer to it.
Reference:
Patent; ASTRAZENECA AB; ASTRAZENECA UK LIMITED; WO2009/22185; (2009); A2;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia