Adding a certain compound to certain chemical reactions, such as: 1195-08-0, 2,4-Dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Safety of 2,4-Dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde, blongs to pyrimidines compound. Safety of 2,4-Dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde
General procedure: To a solution of the pseudothiohydantoin 6a (139 mg, 1.2 mmol), and sodium acetate (328 mg, 4.0 mmol) in acetic acid (5 ml) was added 5-phenyl-2-furaldehyde 5a (172 mg,1.0 mmol) at 25C. The solution was refluxed at 135C for 12 h. The precipitate was filtered and washed with water and diethyl ether. The filter cake was dried under high vacuum to afford 230 mg (85%) of compound 7a as an orange solid.
The synthetic route of 1195-08-0 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Jung, Michael E.; Ku, Jin-Mo; Du, Liutao; Hu, Hailiang; Gatti, Richard A.; Bioorganic and Medicinal Chemistry Letters; vol. 21; 19; (2011); p. 5842 – 5848;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia