New learning discoveries about 4-Amino-6-bromopyrimidine

At the same time, in my other blogs, there are other synthetic methods of this type of compound,1159818-57-1, 4-Amino-6-bromopyrimidine, and friends who are interested can also refer to it.

Adding a certain compound to certain chemical reactions, such as: 1159818-57-1, 4-Amino-6-bromopyrimidine, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, SDS of cas: 1159818-57-1, blongs to pyrimidines compound. SDS of cas: 1159818-57-1

To a solution of 6-bromopyrimidin-4-amine (8.0 g, 46 mmol) in 100 mL of HI was added Nal (15.0 g, 100 mmol). The mixture was refluxed overnight. Then, the mixture was adjusted to pH=10 with NaOH solution, and the solid was separated and filtered to give 6-iodopyrimidin-4-amine. 1H NMR (400Mz, DMSO-d6) 56.85 (s, 1 H), 6.99(s, 2H), 7.99 (s, 1 H).

At the same time, in my other blogs, there are other synthetic methods of this type of compound,1159818-57-1, 4-Amino-6-bromopyrimidine, and friends who are interested can also refer to it.

Reference:
Patent; SYNGENTA PARTICIPATIONS AG; EDMUNDS, Andrew; RENDLER, Sebastian; MUEHLEBACH, Michel; EMERY, Daniel; (109 pag.)WO2018/206348; (2018); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia