Related Products of 5267-07-2, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 5267-07-2, name is 5-Pyrimidineacetic acid. This compound has unique chemical properties. The synthetic route is as follows.
To a solution of 4-bromobenzene-l ,2-diamine (10) (0.281g, 1.5mmol) , 2-(pyrimidin-5-yl)acetic acid (11) (0.207g, 1.5mmol), and HATU (0.741g, 1.95mmol) in DCM (50ml) was added triethylamine (0.63ml, 4.5mmol). The reaction mixture was stirred at room temperature overnight. The solution was washed with saturated sodium bicarbonate (50ml) and brine (50ml). The DCM solution was dried over sodium sulfate and concentrated. The residue was purified by automated column chromatography columned using DCM and methanol as eluents. Yield 0.4g, 87%. MS: m/z 306.9 (M+H+).
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 5267-07-2, 5-Pyrimidineacetic acid.
Reference:
Patent; ZALICUS PHARMACEUTICALS LTD.; PAJOUHESH, Hassan; HOLLAND, Richard; ZHANG, Lingyun; PAJOUHESH, Hossein; LAMONTAGNE, Jason; WHELAN, Brendan; WO2012/116440; (2012); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia