Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps,and cheap raw materials. 504-17-6, name is 4,6-Dihydroxy-2-mercaptopyrimidine. A new synthetic method of this compound is introduced below., 504-17-6
General procedure: Fe3O4(aT)Ph-PMO-NaHSO4 (30 mg) was added to amixture of aromatic aldehyde (1 mmol), malononitrile (1 mmol) and barbituric or thiobarbituric acid (1 mmol)in water (3 mL). Then the mixture was heated at 80 Cin appropriate times and the progress of the reaction wasindicated by TLC (n-hexane:ethyl acetate; 3:7). With completingthe reaction, 3 ml ethanol was poured and the magneticnanocomposite was separated in the presence of amagnetic stirring bar; the reaction mixture became clearand the crude product was recrystallized from ethanol togive the pure product. The pure products were characterizedby conventional spectroscopic methods. Physical andspectral data for selected compound are represented below.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,504-17-6, 4,6-Dihydroxy-2-mercaptopyrimidine, and friends who are interested can also refer to it.
Reference:
Article; Haghighat, Mahdieh; Shirini, Farhad; Golshekan, Mostafa; Journal of Nanoscience and Nanotechnology; vol. 19; 6; (2019); p. 3447 – 3458;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia