New learning discoveries about Perchloropyrimido[5,4-d]pyrimidine

According to the analysis of related databases, 32980-71-5, the application of this compound in the production field has become more and more popular.

Application of 32980-71-5, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 32980-71-5, name is Perchloropyrimido[5,4-d]pyrimidine. This compound has unique chemical properties. The synthetic route is as follows.

2M Ethylamine/THF (27 mL, 54.00 mmol) was added dropwise to a solution of 2,4,6,8-tetrachloro-pyrimido[5,4-djpyrimidine (1)(3.00 g, 11.15 mmol) in THF (150 mL) at 0C. The reaction mixture was stirred at room temperature for 2 h. The volatiles were removed and the residue was suspended in water (50 mL). The resultanthe precipitate were filtered, washed with water (2 x 30 mL) and dried over solid P205 to give 2,6-dichloro-N,N?-diethyl-pyrimido [5,4-djpyrimidine-4,8-diamine (160) (2.93 g, 92% yield). 300 MHz ?HNMR (DMSO-d6, ppm): 8.68 (2H, t, J=5.9 Hz) 3.52-3.40 (4H, m) 1.16 (6H, t, J7.1 Hz).ESI-MS (m/z): 287, 289, 291 [M+Hjt

According to the analysis of related databases, 32980-71-5, the application of this compound in the production field has become more and more popular.

Reference:
Patent; GALLEON PHARMACEUTICALS, INC.; DAX, Scott L.; MENCEL, James Joseph; OZOLA, Vita; SUNA, Edgars; SHUBIN, Kirill; (294 pag.)WO2017/3822; (2017); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia