Reactions of β-sulfenyl α,β-unsaturated ketones with guanidine, amidines, and diamines was written by Nishio, Takehiko;Tokunaga, Tatsuhiro;Omote, Yoshimori. And the article was included in Journal of Heterocyclic Chemistry in 1985.SDS of cas: 40230-24-8 This article mentions the following:
Cyclocondensation of RCOCH:CR1SR2 (I, R = Ph, R1 = Me, R2 = Et; R = R1 = Me, R2 = Ph; R = R1 = Ph, R2 = Et) with R3C(:NH)NH2 (R3 = NH2, Me, Ph) gave pyrimidine derivatives in 14-76% yields. Cyclocondensation of I with ethylenediamine or o-(H2N)2C6H4 afforded 1,4-diazepines. In the experiment, the researchers used many compounds, for example, 4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8SDS of cas: 40230-24-8).
4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8) belongs to pyrimidine derivatives. Heterocyclic compounds bearing the pyrimidine core are of tremendous interest as they constitute an important class of natural and synthetic compounds exhibiting diverse useful biological activities that hold attractive potential for clinical translation as therapeutic agents in alleviation of a myriad of diseases. For example, the neurotoxin tetrodotoxin is a pyrimidine derivative. It is found in a number of species including the Japanese puffer fish, the blue-ringed octopus, and the orange-bellied newt. Tetrodotoxin prevents the transmission of nerve signals and can result in paralysis and death.SDS of cas: 40230-24-8
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia