O’Brien, Darrell E’s team published research in Journal of Heterocyclic Chemistry in 1967 | 15837-41-9

Journal of Heterocyclic Chemistry published new progress about Mannich reaction. 15837-41-9 belongs to class pyrimidines, and the molecular formula is C4H4N2O2, Category: pyrimidines.

O’Brien, Darrell E.; Weinstock, Louis T.; Springer, Robert H.; Cheng, Chia-Chung published the artcile< Pyrimidines. XIX. Pyrimidol[4,5 - e]dihydro - 1,3-oxazines and related compounds>, Category: pyrimidines, the main research area is PYRIMIDO DIHYDRO OXAZINES; OXAZINES PYRIMIDO DIHYDRO.

A number of 2-substituted 4,5-dihydroxy-6-(substituted aminomethyl)pyridimines (I) were prepared from the corresponding 2-substituted 4,5-dihydroxypyrimidines by a new pyrimidine Mannich reaction. The structure of I was proved by an independent synthesis. Further study of this reaction led to the synthesis of pyrimido[4,5-e]dihydro-1,3-oxazines (II). 24 references.

Journal of Heterocyclic Chemistry published new progress about Mannich reaction. 15837-41-9 belongs to class pyrimidines, and the molecular formula is C4H4N2O2, Category: pyrimidines.

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia