On August 27, 2004, Ondi, Levente; Lefebvre, Olivier; Schlosser, Manfred published an article.SDS of cas: 785777-98-2 The title of the article was Brominated 4-(trifluoromethyl)pyrimidines: A convenient access to versatile intermediates. And the article contained the following:
An expedient route to all three monobrominated and all three dibrominated isomers of 4-(trifluoromethyl)pyrimidine, and to several other halogenated pyrimidines, is described. Key steps are the electrophilic introduction of the halogen in the 5-position of 2- or 4-pyrimidinones, the bromodeoxygenation of pyrimidinones or thiopyrimidinones using phosphorus tribromide, and the partial debromination of dibromo-4-(trifluoromethyl)pyrimidines. The experimental process involved the reaction of 2,5-Dichloro-4-(trifluoromethyl)pyrimidine(cas: 785777-98-2).SDS of cas: 785777-98-2
The Article related to brominated trifluoromethylpyrimidine preparation, pyrimidine trifluoromethyl bromo preparation, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.SDS of cas: 785777-98-2
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia