On August 22, 2012, Ouyang, Wuqing; Zheng, Xingxing; Ouyang, Shenyu published a patent.Computed Properties of 23256-42-0 The title of the patent was Preparation of pharmaceutical nanoemulsion composition containing erythromycin ethylsuccinate used as antibacterial agent. And the patent contained the following:
The title composition with particle size of 1-100 nm contains (by weight%) erythromycin ethylsuccinate 0.2-4, trimethoprim lactate 0.03-1, surfactant 25-38, cosurfactant 2-11, oil 2.5-9.8% and distilled water as balance. The surfactant is Tween-80, RH-40 or EL-40. The cosurfactant is anhydrous ethanol, 1,2-propylene glycol, isopropanol and/or polyethylene glycol 600. The oil is carvacrol, cinnamaldehyde, iso-Pr myristate and/or triacetin. The preparation method comprises the steps of: (1) dissolving erythromycin ethylsuccinate with oil and cosurfactant to obtain a oil phase, (2) dissolving trimethoprim lactate with distilled water to obtain a water phase, and (3) stirring the oil phase and surfactant at room temperature while dripping the water phase, and stirring to obtain clear and transparent solution The inventive nanoemulsion can be used for treating mycoplasma pneumonia, urogenital tract infection, pertussis, skin and soft tissue infection, and respiratory tract infection induced by sensitive organism. The experimental process involved the reaction of 5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diamine 2-hydroxypropanoate(cas: 23256-42-0).Computed Properties of 23256-42-0
The Article related to erythromycin ethylsuccinate nanoemulsion antibacterial agent, Pharmaceuticals: Formulation and Compounding and other aspects.Computed Properties of 23256-42-0
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia