Pyrimidines

Efficient and convenient preparation of 3-aryl-2,2-dimethylpropanoates via Negishi coupling was written by Kwak, Young-Shin;Kanter, Aaron D.;Wang, Bing;Liu, Yugang. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2009.HPLC of Formula: 62968-37-0 This article mentions the following:

An efficient and convenient Negishi coupling protocol was developed for the preparation of 3-aryl-2,2-dimethylpropanoates providing easy access to key pharmaceutical intermediates that often require multi-step synthesis using conventional enolate chem. In the experiment, the researchers used many compounds, for example, 4-(2-Chloropyrimidin-4-yl)morpholine (cas: 62968-37-0HPLC of Formula: 62968-37-0).

4-(2-Chloropyrimidin-4-yl)morpholine (cas: 62968-37-0) belongs to pyrimidine derivatives. Heterocyclic compounds bearing the pyrimidine core are of tremendous interest as they constitute an important class of natural and synthetic compounds exhibiting diverse useful biological activities that hold attractive potential for clinical translation as therapeutic agents in alleviation of a myriad of diseases. Drugs having the pyrimidine motif have manifested to exhibit gratifying biological activity like anticancer, antiviral, anti-inflammatory, antibacterial, and antihypertensive activities.HPLC of Formula: 62968-37-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

A general asymmetric copper-catalysed Sonogashira C(sp³)-C(sp) coupling was written by Dong, Xiao-Yang;Zhang, Yu-Feng;Ma, Can-Liang;Gu, Qiang-Shuai;Wang, Fu-Li;Li, Zhong-Liang;Jiang, Sheng-Peng;Liu, Xin-Yuan. And the article was included in Nature Chemistry in 2019.Related Products of 37972-24-0 This article mentions the following:

Continued development of the Sonogashira coupling has made it a well established and versatile reaction for the straightforward formation of C-C bonds, forging the carbon skeletons of broadly useful functionalized mols. However, asym. Sonogashira coupling, particularly for C(sp³)-C(sp) bond formation, has remained largely unexplored. Here the authors demonstrate a general stereoconvergent Sonogashira C(sp³)-C(sp) cross-coupling of a broad range of terminal alkynes and racemic alkyl halides (>120 examples) that are enabled by copper-catalyzed radical-involved alkynylation using a chiral cinchona alkaloid-based P,N-ligand. Industrially relevant acetylene and propyne are successfully incorporated, laying the foundation for scalable and economic synthetic applications. The potential utility of this method is demonstrated in the facile synthesis of stereoenriched bioactive or functional mol. derivatives, medicinal compounds and natural products that feature a range of chiral C(sp³)-C(sp/sp²/sp³) bonds. This work emphasizes the importance of radical species for developing enantioconvergent transformations. In the experiment, the researchers used many compounds, for example, 2-Ethynylpyrimidine (cas: 37972-24-0Related Products of 37972-24-0).

2-Ethynylpyrimidine (cas: 37972-24-0) belongs to pyrimidine derivatives. Pyrimidine is an aromatic heterocyclic organic compound similar to pyridine. For example, the neurotoxin tetrodotoxin is a pyrimidine derivative. It is found in a number of species including the Japanese puffer fish, the blue-ringed octopus, and the orange-bellied newt. Tetrodotoxin prevents the transmission of nerve signals and can result in paralysis and death.Related Products of 37972-24-0

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Deciphering of antibiotic resistance genes and potential abiotic indicators for emergence of antibiotic resistance genes in interconnected lake-river-reservoir system was written by Zhang, Yongpeng;Shen, Genxiang;Hu, Shuangqing;He, Yiliang;Li, Peng;Zhang, Bo. And the article was included in Journal of Hazardous Materials in 2021.Recommanded Product: 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide This article mentions the following:

This study aimed to decipher the patterns of antibiotic resistance genes (ARGs) and linkages of key abiotic indicators with ARGs in an interconnected lake-river-reservoir system. The results showed that seasonal variations in the relative abundance of ARGs and mobile gene elements (MGEs) were significant (KW, p < 0.05). ARGs representative of fecal pollution and natural environment were primarily distributed in the river and reservoir, resp. The lake, river, and reservoir shared 54.5% of ARGs subtypes, most of which are multidrug resistance genes encoding for efflux pumps. Network results showed that ARGs conferring resistance to aminoglycoside frequently co-occurred with class 1 integrons and Limnohabitans. The resistance risks were low and associated with non-corresponding ARGs, and the highest resistance risk was caused by enrofloxacin in the Dianshan Lake. Fluorescence indexes derived from two methods exhibited consistent pos. correlations with abundance of individual genes (i.e. aada1 and aadA2-03) as well as total aminoglycoside resistance genes (Pearson, p < 0.05). Moreover, ARGs indicators of human and animal fecal pollution showed linkages with humic-like and fulvic-like indexes (Pearson, p < 0.05). The results provide novel insights into the roles of abiotic factors on indicating dynamics of ARGs in aquatic environment impacted by anthropogenic activities. In the experiment, the researchers used many compounds, for example, 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3Recommanded Product: 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide).

4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3) belongs to pyrimidine derivatives. The aromatic compound pyrimidine, and its derivatives, are ubiquitous in nature. They are found in nucleic acids, vitamins, amino acids, antibiotics, alkaloids, and a variety of toxins. For example, the neurotoxin tetrodotoxin is a pyrimidine derivative. It is found in a number of species including the Japanese puffer fish, the blue-ringed octopus, and the orange-bellied newt. Tetrodotoxin prevents the transmission of nerve signals and can result in paralysis and death.Recommanded Product: 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Easy synthesis of new series of pteridine analogs: di- and tetra-hydropyrimido[4,5-d]pyrimidines via 5-pyrimidinecarbaldehydes was written by de la Torre, Jose M.;Nogueras, Manuel;Borkowski, Eduardo J.;Suvire, Fernando D.;Enriz, Ricardo D.;Cobo, Justo. And the article was included in ARKIVOC (Gainesville, FL, United States) in 2014.Quality Control of 6-Amino-3-methyl-2-(methylthio)pyrimidin-4(3H)-one This article mentions the following:

Pyrimidine-5-carbaldehyde derivatives, of easy access, were selected as precursors for the synthesis of mimic pteridine derivatives 5,6-dihydropyrimido[4,5-d]pyrimidines I [R¹ = C₆H₅, CH₂C₆H₅, C₆H₁₁, CH(CH₃)C₆H₅; R² = H, CH₃; X = O, S] and 5,6,7,8- tetrahydropyrimido[4,5-d]pyrimidines II (R³ = H, CH₃, C₆H₅) via 4-amino-(5-aminomethyl)pyrimidine intermediates. Straightforward procedures allow a quick access to these compounds The dihydro derivatives were prepared means of a final cyclocondensation carried out with orthoesters R²R³C(O), catalyzed by acid and assisted by microwaves irradiation under solvent-free conditions. The final cyclocondensation with carbonyl compounds forming the tetrahydro derivatives was done under mild conditions, in which stereochem. induction was carried out on the building of this skeleton, and stereochem. assignments corroborated by theor. calculations In the experiment, the researchers used many compounds, for example, 6-Amino-3-methyl-2-(methylthio)pyrimidin-4(3H)-one (cas: 54030-56-7Quality Control of 6-Amino-3-methyl-2-(methylthio)pyrimidin-4(3H)-one).

6-Amino-3-methyl-2-(methylthio)pyrimidin-4(3H)-one (cas: 54030-56-7) belongs to pyrimidine derivatives. The aromatic compound pyrimidine, and its derivatives, are ubiquitous in nature. They are found in nucleic acids, vitamins, amino acids, antibiotics, alkaloids, and a variety of toxins. Pyrimidine derivatives have been used in a wide variety of pharmaceuticals including general anesthetics, anti-epilepsy medication, anti-malaria medication, drugs for treating high blood pressure, and HIV medication.Quality Control of 6-Amino-3-methyl-2-(methylthio)pyrimidin-4(3H)-one

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

High-density Si nanopillars modified with Ag nanoislands: Sensitive SALDI-MS chip for sulfonamides was written by Dou, Shuzhen;Lu, Jiaxin;Chen, Qiye;Chen, Chunning;Lu, Nan. And the article was included in Sensors and Actuators, B: Chemical in 2022.Safety of 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide This article mentions the following:

In recent years, the abuse of antibiotics has brought adverse effects on water environment and food safety, to monitor the antibiotic content in water and foodstuffs is imperative for environmental protection and human health. In this work, a chip, composed of high-d. Si nanopillars and Ag nanoislands, is prepared for sensitive detection of sulfonamides with surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS). In this chip, the high-d. Si nanopillars can absorb laser energy efficiently and promote electron transfer as antennas; the Ag nanoislands can enhance the thermal effect; the formation of the Schottky barrier and the conductive nanolayer between Si/Ag can extend the lifetime of electrons and promote electron tunneling effect. Therefore, the heterostructure presents high detection sensitivity (the limit of detection of sulfamethazine is as low as 3 amol); in addition, the satisfactory coefficients of determination (> 0.99) show that the chip is applicable for rapid quantification of sulfonamides. Further, the sulfacetamides spiked in milk and lake water can be sensitively identified and rapidly quantified. The prepared chip presents a considerable potential for food and environment monitoring. In the experiment, the researchers used many compounds, for example, 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3Safety of 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide).

4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3) belongs to pyrimidine derivatives. Pyrimidines are isomeric with two other forms of diazines: pyridazine, with the nitrogen atoms in the 1 and 2 positions; and pyrazine, with the nitrogen atoms in the 1 and 4 positions. For example, the neurotoxin tetrodotoxin is a pyrimidine derivative. It is found in a number of species including the Japanese puffer fish, the blue-ringed octopus, and the orange-bellied newt. Tetrodotoxin prevents the transmission of nerve signals and can result in paralysis and death.Safety of 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Spatiotemporal distribution, source apportionment and combined pollution of antibiotics in natural waters adjacent to mariculture areas in the Laizhou Bay, Bohai Sea was written by Han, Q. F.;Song, C.;Sun, X.;Zhao, S.;Wang, S. G.. And the article was included in Chemosphere in 2021.Safety of 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide This article mentions the following:

The spatiotemporal distribution, source apportionment and combined pollution of 14 antibiotics in natural waters adjacent to mariculture farms of Laizhou Bay in the Bohai Sea were studied. The contribution proportion and quantity of each potential pollution source to antibiotics in natural water bodies were quant. described. The correlations between heavy metals and antibiotics and their underlying mechanisms in natural and aquaculture water environment were analyzed. Fourteen antibiotics were detected in natural water and sediment in the coastal area of Laizhou Bay. The maximum concentrations of sulfamethazine and trimethoprim in water reached tens or even hundreds of 娓璯/L in winter. Trimethoprim was the main antibiotic in natural water bodies in winter and summer, and enrofloxacin was the principal antibiotic in sediments. Enrofloxacin, ciprofloxacin and oxytetracycline were detected in all underground water samples; thus, control of these antibiotics needs to be made a priority to mitigate groundwater contamination. PCA-MLR revealed that the potential sources of antibiotics in natural waters of Laizhou Bay include the mariculture wastewater (18.3%), the domestic sewage (63.3%) and the livestock wastewater (18.4%). Therefore, the antibiotic burden of Laizhou Bay was principally from the domestic sewage. In natural water, the concentration of Cu was pos. correlated with antibiotics, which might be related to the common sources, the competitive adsorption in sediments and the easy complexation characteristic of Cu and antibiotics. Pos. correlations among antibiotics and heavy metals were observed in mariculture sediments, while neg. relationships were observed in natural sediments. In the experiment, the researchers used many compounds, for example, 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3Safety of 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide).

4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3) belongs to pyrimidine derivatives. The pyrimidine ring system has wide occurrence in nature as substituted and ring fused compounds and derivatives. Pyrimidine derivatives also play an important role in drug development, either in concert with other compounds or on their own.Safety of 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Production of a Natural Dihydropteroate Synthase and Development of a Signal-Amplified Pseudo-Immunoassay for the Determination of Sulfonamides in Pork was written by He, Tong;Cui, Peng Lei;Liu, Jing;Feng, Cheng;Wang, Jian Ping. And the article was included in Journal of Agricultural and Food Chemistry in 2022.Safety of 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide This article mentions the following:

In this study, a type of magnetic photoaffinity-labeled activity-based protein profiling probe for sulfonamide drugs was first synthesized for the purpose of capturing the natural dihydropteroate synthase of Escherichia coli by using simple incubation and magnetic separation After characterization of its identity with LC-ESI-MS/MS, this enzyme was used as a recognition reagent to develop a direct competitive pseudo-ELISA for the determination of the residues of 40 sulfonamides in pork. Because of the use of streptavidin-horseradish peroxidase and biotinylated horseradish peroxidase as a signal-amplified system, the limits of detection for the 40 drugs were in the range of 0.001-0.016 ng/mL. Compared to the steps in a conventional assay formation, the operation steps were the same, but the sensitivities increased 32-88-fold. Furthermore, the assay performances were better than the previously reported immunoassays performances for sulfonamides. Therefore, this method could be used as a practical tool for multiscreening the trace levels of sulfonamides residues in food samples. In the experiment, the researchers used many compounds, for example, 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3Safety of 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide).

4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide (cas: 1220-83-3) belongs to pyrimidine derivatives. Heterocyclic compounds bearing the pyrimidine core are of tremendous interest as they constitute an important class of natural and synthetic compounds exhibiting diverse useful biological activities that hold attractive potential for clinical translation as therapeutic agents in alleviation of a myriad of diseases. As nucleotides in DNA and RNA, pyrimidine nucleotide derivatives have a wide range of biological applications. For example, pyrimidine derivatives are useful in DNA repair studies involving cancer and epigenetics.Safety of 4-Amino-N-(6-methoxypyrimidin-4-yl)benzenesulfonamide

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Synthesis and biological evaluation of pyrimidine bridged combretastatin derivatives as potential anticancer agents and mechanistic studies was written by Kumar, Bhupinder;Sharma, Praveen;Gupta, Vivek Prakash;Khullar, Madhu;Singh, Sandeep;Dogra, Nilambra;Kumar, Vinod. And the article was included in Bioorganic Chemistry in 2018.HPLC of Formula: 40230-24-8 This article mentions the following:

A number of pyrimidine bridged combretastatin derivatives were designed, synthesized and evaluated for anticancer activities against breast cancer (MCF-7) and lung cancer (A549) cell lines using MTT assays. Most of the synthesized compounds displayed good anticancer activity with IC₅₀ values in low micro-molar range. Compounds I and II were found most potent in the series with IC₅₀ values of 4.67 娓璏 & 3.38 娓璏 and 4.63 娓璏 & 3.71 娓璏 against MCF7 and A549 cancer cell lines, resp. Biol. evaluation of these compounds showed that selective cancer cell toxicity (in vitro using human lung and breast cancer cell lines) might be due to the inhibition of antioxidant enzymes instigating elevated ROS levels which triggers intrinsic apoptotic pathways. These compounds were found nontoxic to the normal human primary cells. Compound I, was found to be competitive inhibitor of colchicine and in the tubulin binding assay it showed tubulin polymerization inhibition potential comparable to colchicine. The mol. modeling studies also showed that the synthesized compounds fit well in the colchicine-binding pocket. In the experiment, the researchers used many compounds, for example, 4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8HPLC of Formula: 40230-24-8).

4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8) belongs to pyrimidine derivatives. Pyrimidines are isomeric with two other forms of diazines: pyridazine, with the nitrogen atoms in the 1 and 2 positions; and pyrazine, with the nitrogen atoms in the 1 and 4 positions. For example, the neurotoxin tetrodotoxin is a pyrimidine derivative. It is found in a number of species including the Japanese puffer fish, the blue-ringed octopus, and the orange-bellied newt. Tetrodotoxin prevents the transmission of nerve signals and can result in paralysis and death.HPLC of Formula: 40230-24-8

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Investigation in the pyrimidine series V. Acylation of 6-amino-4-oxodihydropyrimidines was written by Pfleiderer, Wolfgang;Liedek, Egon. And the article was included in Justus Liebigs Annalen der Chemie in 1957.Synthetic Route of C6H9N3OS This article mentions the following:

Acylation in the 6-amino-4-oxodihydropyrimidine system occurred in normal fashion on the amino group, as determined by synthesis and by ultraviolet spectral data. NH.CS.NH.CO.CH:CNH₂ (I) (14.3 g.) dissolved in 140 cc. H₂O and 14 cc. concentrated NH₄OH by warming, 42 g. Raney Ni added portionwise at 80鎺? the mixture refluxed 3 hrs., filtered hot, the filtrate kept several hrs. in the refrigerator, the precipitate (II) filtered off, the filtrate concentrated to furnish a 2nd fraction (III), and II and III combined and recrystallized from H₂O gave 6.7 g. N:CH.NH.CO.CH:CNH₂ (IV), m. 271-2鎺?(decomposition). IV (5 g.) and 50 cc. Ac₂ refluxed 30 min., cooled, and the precipitate collected (addnl. material by concentrating the filtrate) and recrystallized from H₂O gave 5.4 g. 6-AcNH analog (V), m. 288-9鎺? I (57 g.) in 600 cc. 2N NaOH treated slowly at 40鎺?with 150 cc. Me₂SO₄ with stirring (a pH of 9 maintained toward the end of the methylation), the precipitate filtered off after 6 hrs., dried, digested with Et₂O, filtered off, and recrystallized from H₂O gave 48 g. N:C(SMe).NMe.CO.CH:CNH₂ (VI), m. 257鎺? VI (17.1 g.) and 120 cc. Ac₂O refluxed 30 min., cooled, the precipitate collected, and recrystallized from aqueous EtOH gave 9.2 g. 6-AcNH analog (VII), m. 251鎺? To 17.1 g. VI in 400 cc. H₂O was added 17.1 g. Raney Ni at 80鎺? refluxed 3.5 hrs., filtered hot, the filtrate concentrated to 1/3 its volume, the concentrate kept several hrs. in the refrigerator, the precipitate filtered off, and recrystallized from H₂O to give 6.5 g. N:CH.NMe.CO.CH:CNH₂ (VIII), m. 184-5鎺? III (3.7 g.) in 25 cc. 2N NaOH treated dropwise at 40鎺?with 5 cc. Me₂SO₄ with stirring while maintaining a pH of 9 at all times, the mixture neutralized with AcOH, extracted continuously 8 hrs. with CHCl₃, the extract dried, evaporated, and the residue recrystallized from H₂O gave 1.3 g. VIII. V (3.8 g.) in 40 cc. N NaOH treated as above with 4 cc. Me₂SO₄ gave 2.1 g. N:CH.NMe.CO.CH:CNHAc (IX), m. 303-4鎺? VIII (4.1 g.) and 20 cc. Ac₂O refluxed 15 min., cooled, the precipitate filtered off, and crystallized from H₂O gave 3 g. IX. VII (7.1 g.) in 200 cc. H₂O treated portionwise with 50 g. Raney Ni, refluxed 4 hrs., filtered hot, the filtrate concentrated to 1/3 its volume, cooled, the precipitate collected, and crystallized from H₂O gave 4.5 g. IX. N:CS.NH.CO.CMe:CNH₂ (15.7 g.) in 200 cc. H₂O treated with 45 g. Raney Ni, refluxed 4 hrs., filtered hot, the filtrate cooled several hrs. in ice, and the precipitate crystallized from H₂O gave 10 g. N:CH.NH.CO.CMe:CNH₂ (X), m. 243鎺? X (3.1 g.) and 9 cc. Ac₂O refluxed 15 min., cooled, and the precipitate recrystallized from H₂O gave 2 g. 6-AcNH analog, m. 303鎺? In the experiment, the researchers used many compounds, for example, 6-Amino-3-methyl-2-(methylthio)pyrimidin-4(3H)-one (cas: 54030-56-7Synthetic Route of C6H9N3OS).

6-Amino-3-methyl-2-(methylthio)pyrimidin-4(3H)-one (cas: 54030-56-7) belongs to pyrimidine derivatives. Pyrimidine also found in many synthetic compounds such as barbiturates and the HIV drug, zidovudine. Pyrimidine derivatives have been used in a wide variety of pharmaceuticals including general anesthetics, anti-epilepsy medication, anti-malaria medication, drugs for treating high blood pressure, and HIV medication.Synthetic Route of C6H9N3OS

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia

Reaction of N-(carbamimidoyl)thiourea with 1-benzoyl-2-phenylacetylene was written by Glotova, T. E.;Dvorko, M. Yu.;Albanov, A. I.;Protsuk, N. I.. And the article was included in Russian Journal of Organic Chemistry in 2007.SDS of cas: 40230-24-8 This article mentions the following:

1-Benzoyl-2-phenylacetylene reacted with N-(carbamimidoyl)thiourea H₂NC(:S)NHC(:NH)NH₂ in glacial acetic acid saturated with 20% HBr to give (4,6-diphenyl-2H-1,3-thiazin-2-ylidene)guanidine hydrobromide. The reaction of the same compounds in anhydrous EtOH in the presence of NaOEt led to the formation of N-(4,6-diphenylpyrimidin-2-yl)thiourea. Bis(3-oxo-1,3-diphenylprop-1-en-1-yl) sulfide and 1-benzoyl-2-ethylsulfanyl-2-phenylethylene were isolated in the reactions of 1-benzoyl-2-phenylacetylene with N-(carbamimidoyl)thiourea and N-(carbamimidoyl)-S-ethylisothiuronium bromide, resp., in anhydrous MeOH. In the experiment, the researchers used many compounds, for example, 4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8SDS of cas: 40230-24-8).

4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8) belongs to pyrimidine derivatives. Pyrimidines are isomeric with two other forms of diazines: pyridazine, with the nitrogen atoms in the 1 and 2 positions; and pyrazine, with the nitrogen atoms in the 1 and 4 positions. Drugs having the pyrimidine motif have manifested to exhibit gratifying biological activity like anticancer, antiviral, anti-inflammatory, antibacterial, and antihypertensive activities.SDS of cas: 40230-24-8

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia