On September 7, 1999, Pamukcu, Rifat; Piazza, Gary published a patent.Product Details of 42518-42-3 The title of the patent was Inhibition of neoplastic cells by exposure to thienopyrimidines. And the patent contained the following:
A method for inhibiting growth of neoplastic cells comprises administration of title compounds [I; R1, R2 = H, A, OA, alkenyl, alkynyl, NO2, CF3, halo; R3, R4 = H, A, OA, halo, NO2, amino; R3R4 = OCH2CH2, OCH2O, OCH2CH2O; X = substituted 5-7 membered heterocyclyl, isocyclyl; A = H, alkyl; n = 0-3; with provisos]. Thus, 2,4-dichloro-6-methylthieno[2,3-d]pyrimidine, 3,4-methylenedioxybenzylamine, and Et3N were stirred in CH2Cl2 to give 2-chloro-6-methyl-4-(3,4-methylenedioxybenzylamino)thieno[2,3-d]pyrimidine. The experimental process involved the reaction of 2,4-Dichloro-5,6-dimethylthieno[2,3-d]pyrimidine(cas: 42518-42-3).Product Details of 42518-42-3
The Article related to thienopyrimidine preparation neoplasm inhibitor, precancerous lesion treatment thienopyrimidine preparation, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.Product Details of 42518-42-3
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia