Patel, Navin B. published the artcileSynthesis of newer 5-benzylidene-2,4-thiazolidinediones as potential antimicrobials, Name: 2-Amino-4,6-dichloropyrimidine, the publication is Indian Journal of Research in Pharmacy and Biotechnology (2014), 2(1), 993-1001, 9 pp., database is CAplus.
A series of 5-benzylidene-2,4-thiazolidinediones I (R = 5-methylthiazol-2-ylamino, 6-fluorobenzothiazol-2-ylamino, 6-nitrobenzothiazol-2-ylamino, etc.) were synthesized and evaluated for antimycobacterial and antimicrobial activity. In vitro antimycobacterial activity was carried out against (M. tuberculosis) H37Rv strain using Lowenstein-Jensen medium and antimicrobial activity against two Gram pos. bacteria (S. aureus, S. pyogenes), two Gram neg. bacteria (E. coli, P. aeruginosa) and three fungal species (C. albicans, A. niger, A. clavatus) using the broth microdilution method. The compounds I (R = 5-methylthiazol-2-amino, 6-fluorobenzothiazol-2-ylamino, 4-nitrobenzothiazol-2-ylamino, 5-nitrobenzothiazol-2-ylamino, 6-methylbenzothiazol-2-ylamino, 4,6-dimethoxypyrimidin-2-ylamino) exhibited promising antimicrobial activity, whereas compounds I (R = 6-methylbenzothiazol-2-ylamino) showed very good antimycobacterial activity.
Indian Journal of Research in Pharmacy and Biotechnology published new progress about 56-05-3. 56-05-3 belongs to pyrimidines, auxiliary class Pyrimidine,Chloride,Amine,API, name is 2-Amino-4,6-dichloropyrimidine, and the molecular formula is C4H3Cl2N3, Name: 2-Amino-4,6-dichloropyrimidine.
Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/Pyrimidine,
Pyrimidine – Wikipedia