On August 20, 2021, Peach, Jesse T.; Wilson, Stephanie M.; Gunderson, Logan D.; Frothingham, Lizzi; Tran, Tan; Walk, Seth T.; Yeoman, Carl J.; Bothner, Brian; Miles, Mary P. published an article.HPLC of Formula: 4433-40-3 The title of the article was Temporal metabolic response yields a dynamic biosignature of inflammation. And the article contained the following:
Chronic low-grade inflammation is a subclin. condition directly and indirectly linked to the development of a wide range of diseases responsible for the vast majority of morbidity. To examine mechanisms coupled to chronic disease, a group of overweight and obese human subjects without known inflammatory diseases participated in a high-fat meal challenge as an acute inflammation stimulus. Anal. of serum metabolites grouped by baseline cytokine levels revealed that single samples had little power in differentiating groups. However, an anal. that incorporated temporal response separated inflammatory response phenotypes and allowed us to create a metabolic signature of inflammation which revealed metabolic components that are crucial to a cytokine-mediated inflammation response. The use of temporal response, rather than a single time point, improved metabolomic prediction of high postprandial inflammation responses and led to the development of a dynamic biosignature as a potential tool for stratifying risk to a wide range of diseases. The experimental process involved the reaction of 5-(Hydroxymethyl)pyrimidine-2,4(1H,3H)-dione(cas: 4433-40-3).HPLC of Formula: 4433-40-3
The Article related to metabolic response biosignature inflammation, metabolomics, pathophysiology, systems biology, Placeholder for records without volume info and other aspects.HPLC of Formula: 4433-40-3
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia