Pithova, P.; Sorm, F. published the artcile< Influence of some derivatives and structural analogs of pyrimidine and purine bases on the degradation of uracil>, Safety of 6-Bromo-1,2,4-triazine-3,5(2H,4H)-dione, the main research area is .
The enzymic degradation of uracil (I) by rat liver Me2CO powder is inhibited by compounds possessing the NHCONH grouping in a 6-membered ring. Their activity, however, disappears on methylation of N. Xanthine, uric acid, orotie acid, 2-pyridone, and 5-bromo-6-azauracil inhibit the 1st stage of I degradation, viz., its reduction to dihydrouraeil (II). The inhibitory action of 5-substituted I derivatives is apparently of competitive character. None of the above compounds, however, inhibits the degradation of II and no accumulation of β-ureidopropionie acid and β-alanine was detected in the reaction mixture
Collection of Czechoslovak Chemical Communications published new progress about 4956-05-2. 4956-05-2 belongs to class pyrimidines, and the molecular formula is C3H2BrN3O2, Safety of 6-Bromo-1,2,4-triazine-3,5(2H,4H)-dione.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia