Pluskota, Donata published the artcileThe facile synthesis of N(1), N(4)-dimethyl-5-substituted cytosines, Related Products of pyrimidines, the main research area is methylcytosine; cytosine alkyldimethyl.
A facile, high yield synthesis of N(1),N(4)-dimethyl-5-alkylcytosines is described. Thus chlorination of alkyluracils I (R = Me, Et, Pr, Bu) followed by substitution with NaOEt and methylation gave methylpyrimidinones II (R1 = EtO). Substitution of II (R1 = EtO) with MeNH2 gave the title compounds II (R1 = MeNH). This method is an alternative and universal route to N(1),N(4)-methylated cytosines with any 5-substituent.
Synthetic Communications published new progress about methylcytosine; cytosine alkyldimethyl. 19030-75-2 belongs to class pyrimidines, name is 5-N-Propyluracil, and the molecular formula is C7H10N2O2, Related Products of pyrimidines.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia