Pola, Suresh; Shah, Shailesh R.; Pingali, Harikishore; Zaware, Pandurang; Thube, Baban; Makadia, Pankaj; Patel, Hoshang; Bandyopadhyay, Debdutta; Rath, Akshyaya; Giri, Suresh; Patel, Jitendra H.; Ranvir, R. K.; Sundar, S. R.; Patel, Harilal; Kumar, Jeevan; Jain, Mukul R. published an article in 2021. The article was titled 《Discovery of a potent G-protein-coupled receptor 119 agonist for the treatment of type 2 diabetes》, and you may find the article in Bioorganic & Medicinal Chemistry.COA of Formula: C4H2Cl2N2 The information in the text is summarized as follows:
Benzylidenethiazolidinedione as a novel polar head for discovering a new series of GPR119 agonists I [R = H, Me; R1 = methoxycarbonyl, ethoxycarbonyl, tert-butoxycarbonyl, isobutoxycarbonyl, benzyloxycarbonyl] was discussed. The identification of a potent and oral GPR 119 agonist II [R = Me; R1 = tert-butoxycarbonyl], which showed in-vitro potency in the cell-based assay and in-vivo efficacy without exerting any significant signs of toxicity in relevant animal models. In the experimental materials used by the author, we found 4,6-Dichloropyrimidine(cas: 1193-21-1COA of Formula: C4H2Cl2N2)
4,6-Dichloropyrimidine(cas: 1193-21-1) is a member of organic chlorides. Organic chloride content in crude oil can be detected through specialized laboratory analysis. Care and attention are essential while sampling and testing.COA of Formula: C4H2Cl2N2
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia