In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Direct Enantio- and Diastereoselective Vinylogous Addition of Butenolides to Chromones Catalyzed by Zn-ProPhenol, published in 2019-01-30, which mentions a compound: 591-12-8, mainly applied to butenolide chromone zinc ProPhenol catalyst enantioselective diastereoselective vinylogous addition; chromanone lactone stereoselective preparation, Formula: C5H6O2.
We report the first enantio- and diastereoselective 1,4-addition of butenolides to chromones. Both α,β- and β,γ-butenolide nucleophiles are compatible with the Zn-ProPhenol catalyst, and preactivation as the siloxyfurans is not required. The scope of electrophiles includes a variety of substituted chromones, as well as a thiochromone and a quinolone, and the resulting vinylogous addition products, e.g. I, are generated in good yield (31 to 98%), diastereo- (3:1 to >30:1), and enantioselectivity (90:10 to 99:1 er). These Michael adducts allow rapid access to several natural product analogs, and can be easily transformed into a variety of other interesting scaffolds as well.
After consulting a lot of data, we found that this compound(591-12-8)Formula: C5H6O2 can be used in many types of reactions. And in most cases, this compound has more advantages.
Reference:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia