Purkayastha, Subhasish; Lazrek, Bihi H.; Panzica, Raymond P.; Naguib, Fardos N. M.; El Kouni, Mahmoud H. published the artcile< as-Triazine acyclonucleosides: potential inhibitors of pyrimidine enzymes>, Synthetic Route of 4956-05-2, the main research area is triazine acyclonucleoside; nucleoside acyclo triazine; pyrimidine enzyme inhibitor acyclonucleoside.
Seven as-triazine-3,5-dione acyclonucleosides I (R = Ac, H, R1 = SCH2Ph, Br, H; R = H, R1 = NH2) were prepared starting with the alkylation of the corresponding O-trimethylsilylated as-triazine-3,5-diones with AcOCH2CH2OCH2Br. I were evaluated as inhibitors of orotate phosphoribosyltransferase (OPRTase, EC 2.4.2.10), orotidine 5′-monophosphate decarboxylase (ODCase, EC 4.1.2.23), uridine phosphorylase (UrdPase, EC 2.4.2.3), and thymidine phosphorylase (dThdPase, EC 2.4.2.4). I did not inhibit any of these enzymes.
Nucleosides & Nucleotides published new progress about 4956-05-2. 4956-05-2 belongs to class pyrimidines, and the molecular formula is C3H2BrN3O2, Synthetic Route of 4956-05-2.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia