A regiospecific three-component one-step cyclocondensation to 6-cyano-5,8-dihydropyrido[2,3-d]pyrimidin-4(3H)-ones using microwaves under solvent-free conditions was written by Quiroga, J.;Cisneros, C.;Insuasty, B.;Abonia, R.;Nogueras, M.;Sanchez, A.. And the article was included in Tetrahedron Letters in 2001.Product Details of 54030-56-7 This article mentions the following:
In a solvent-free system, regiospecific three-component one-step cyclocondensation to dihydropyrido[2,3-d]pyrimidin-4(3H)-ones starting from readily available aminopyrimidin-4(3H)-ones, benzoylacetonitrile and benzaldehydes by microwave radiation was carried out. This rapid method produces pure products in high yields (70-75%). In the experiment, the researchers used many compounds, for example, 6-Amino-3-methyl-2-(methylthio)pyrimidin-4(3H)-one (cas: 54030-56-7Product Details of 54030-56-7).
6-Amino-3-methyl-2-(methylthio)pyrimidin-4(3H)-one (cas: 54030-56-7) belongs to pyrimidine derivatives. The pyrimidine derivatives can easily interact with enzymes, genetic materials, and bio components within the cell. We all know its importance to life – pyrimidine and purine bases are included in the structure of DNA and RNA.Product Details of 54030-56-7
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia