Shock sensitivity of a vinamidinium bis-perchlorate reagent and demonstration of a lower energy alternative was written by Ragan, John A.;McDermott, Ruth E.;Jones, Brian P.;am Ende, David J.;Clifford, Pamela J.;McHardy, Stanton J.;Heck, Steven D.;Liras, Spiros;Segelstein, Barb E.. And the article was included in Synlett in 2000.Product Details of 90905-32-1 This article mentions the following:
“Vinamidinium” bisperchlorate salt [2-dimethylaminomethylene-1,3-bis(dimethylimmonio)-propane bis-perchlorate] (I) possesses remarkably high thermal energy as well as significant shock sensitivity. Because a reported method for preparation of 2,5-disubstituted pyrimidines with I was of interest, the corresponding bis(tetrafluoroborate) salt was equally effective in this transformation. However, use of the bis(tetrafluoroborate) salt was safer with respect to shock sensitivity and energy content, compared to I. I has use as a synthetic reagent in pyrimidine annulations. In the experiment, the researchers used many compounds, for example, 2-Methoxypyrimidine-5-carbaldehyde (cas: 90905-32-1Product Details of 90905-32-1).
2-Methoxypyrimidine-5-carbaldehyde (cas: 90905-32-1) belongs to pyrimidine derivatives. The pyrimidine ring system has wide occurrence in nature as substituted and ring fused compounds and derivatives. Pyrimidine derivatives also play an important role in drug development, either in concert with other compounds or on their own.Product Details of 90905-32-1
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia