CsOH/γ-Al2O3: a heterogeneous reusable basic catalyst for one-pot synthesis of 2-amino-4,6-diaryl pyrimidines was written by Ramana, Amey Nimkar M. M. V.;Betkar, Rahul;Ranade, Prasanna;Mundhe, Balaji. And the article was included in New Journal of Chemistry in 2016.HPLC of Formula: 40230-24-8 This article mentions the following:
New strategy for a one-pot synthesis of 2-amino-4,6-diaryl pyrimidines using CsOH/γ-Al2O3 as a heterogeneous, reusable basic catalyst was presented. Developed synthetic protocol for pyrimidines was a one-pot three-component reaction of acetophenone, aromatic aldehydes and guanidine hydrochloride in ethanol. Characterization of the catalyst CsOH/γ-Al2O3 was performed by using FT-IR, XRD, TG-DTA, SEM, BET surface area and CO2-TPD anal. techniques. Anal. data prove that the catalyst had excellent reusability and also indicated their good thermal stability. In the experiment, the researchers used many compounds, for example, 4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8HPLC of Formula: 40230-24-8).
4,6-Diphenylpyrimidin-2-amine (cas: 40230-24-8) belongs to pyrimidine derivatives. The aromatic compound pyrimidine, and its derivatives, are ubiquitous in nature. They are found in nucleic acids, vitamins, amino acids, antibiotics, alkaloids, and a variety of toxins. Drugs having the pyrimidine motif have manifested to exhibit gratifying biological activity like anticancer, antiviral, anti-inflammatory, antibacterial, and antihypertensive activities.HPLC of Formula: 40230-24-8
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia