Synthetic Route of C8H10N2O2On October 31, 1994 ,《The crafting of uracils with enhanced stacking potential》 appeared in Proceedings – Indian Academy of Sciences, Chemical Sciences. The author of the article were Ranganathan, Subramania; Kundu, Dinabandhu; Mehrotra, Sanjiv. The article conveys some information:
Uracils having enhanced stacking profile are of interest from diverse vantages ranging from the chem. simulation of transcription to the design of novel antiviral agents. This objective has been realized by synthetic strategies leading to uracils having, inter alia, pseudo aromatic and hydrophobic rings crafted to the 5-6 location and ionophore and hydrophobic chains affixed at the C-5 and nitrogen atoms. Endeavors to prepare a 5-2′ uracil-pyrimidine composite have led to novel uracil arising from 2-O → =CH(COOR)2 transformation and a tethered malonic acid pyrimidine complex. The results came from multiple reactions, including the reaction of Ethyl 2-(pyrimidin-2-yl)acetate(cas: 63155-11-3Synthetic Route of C8H10N2O2)
Ethyl 2-(pyrimidin-2-yl)acetate(cas: 63155-11-3) is a member of pyrimidine. Pyrimidine derivatives are an important class of N-heterocycles. They are well-known for their wide spectrum of promising biological activities such as antitumors, bactericidals, and fungicidal.Synthetic Route of C8H10N2O2
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia