The pyrimidine ring system has wide occurrence in nature as substituted and ring fused compounds and derivatives, 109-12-6, formula is C4H5N3, Name is Pyrimidin-2-amine. including the nucleotides cytosine, thymine and uracil, thiamine (vitamin B1) and alloxan. HPLC of Formula: 109-12-6.
Rehan, Thamer A.;Al-Lami, Naeemah;Khudhair, Noor Ali research published 《 Synthesis, characterization and anti-corrosion activity of new triazole, thiadiazole and thiazole derivatives containing imidazo[1,2-a]pyrimidine moiety》, the research content is summarized as follows. In this research, several heterocyclic rings (triazole, thiadiazol, thiazol) containing imidazo (1,2-a) pyrimidine moiety have been prepared via a series of reactions. To do this, synthesis of 2-substituted imidazo (1,2-a) pyrimidine was performed by condensation of 2-aminopyrimidine with (4-bromo phenacyl bromide) or (4-Ph phenacyl bromide). Carbaldehyde group was prepared at position-3 of 2-substituted imidazo/pyrimidine rings by Vilsmeier-Haak reaction. Thiosemicarbazon derivatives (Schiff bases) were synthesized by condensation of 3-carbaldehyde derivatives with thiosemicarbazide. Cyclization of thiosemicarbazone derivatives with Ac2O, 4-bromophenacyl bromide and HCl afforded the corresponding thiadiazole(diacetyl) derivatives, 1,3-thiazole derivatives and 1,2,4-triazole derivatives resp. Structures of the new derivatives were confirmed via FT-IR spectroscopy, some of which were confirmed via 1H-NMR spectroscopy. Three of these new derivatives were evaluated by their anti-corrosion activity.
HPLC of Formula: 109-12-6, 2-Aminopyrimidine is a useful research compound. Its molecular formula is C4H5N3 and its molecular weight is 95.1 g/mol. The purity is usually 95%.
2-Aminopyrimidine is an organic compound that belongs to the group of pyridines. It has been shown to have antimicrobial, antitumor, and antiviral properties. 2-Aminopyrimidine has been used as a fungicide and herbicide in horticulture and agriculture, respectively. The molecular geometry of this molecule is octahedral with coordination geometry C2v. This chemical binds to the BCR-ABL kinase receptor and inhibits its activity by competitive inhibition of ATP binding. 2-Aminopyrimidine has been shown to have a hematologic response in vivo models and in vitro assays. It also has anti-inflammatory effects when it is taken orally or applied topically., 109-12-6.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia