Remennikov, G. Ya.; Kurilenko, L. K.; Boldyrev, I. V.; Cherkasov, V. M. published their research in Khimiya Geterotsiklicheskikh Soedinenii on December 31 ,1987. The article was titled 《Sigma complexes in the pyrimidine series. 8. Recyclization of acetonyl anionic σ-complexes of 5-nitropyrimidine and its derivatives》.SDS of cas: 14001-69-5 The article contains the following contents:
Recyclization of title anions I (R = H, MeO, Et2N; R1 = H; cation not specified) with base, e.g., Et4NOH, gave 19-75% 4-O2NC6H4OH. A bicyclic mechanism was proposed. I (R = H, R1 = OMe) and 2-acetonyl analog II did not recyclize under these conditions. Treating methoxynitropyrimidine III (R = MeO, R2 = H) with Et2NH in refluxing MeOH gave 98% III (R = Et2N, R2 = H) (IV), which gave 68.5% I (R = Et2N, R1 = H) (V) with KOH in Me2CO. Oxidation of V with DDQ in Me2CO gave 43% III (R = Et2N, R2 = CH2COMe) (VI) and 28% IV. Deacylation of acetylacetonylidene analog VII with Et2NH in MeOH gave 74.5% VI and 5% III (R = Et2N, R2 = Me).2-Methoxy-5-nitropyrimidine(cas: 14001-69-5SDS of cas: 14001-69-5) was used in this study.
2-Methoxy-5-nitropyrimidine(cas: 14001-69-5) is a member of ether. Friedel Crafts reaction, for example, adds an alkyl or acyl group to aromatic ethers when they react with an alkyl or acyl halide in the presence of a Lewis acid as a catalyst.SDS of cas: 14001-69-5
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia