Riederer, Heinz; Huettermann, Juergen; Symons, Martyn C. R. published the artcile< Matrix-isolation of free radicals from 5-halouracils. 2. Electron spin resonance of hydrogen atom reactions in acidic glasses>, Electric Literature of 4956-05-2, the main research area is hydrogen atom nucleic acid constituent; nucleoside hydrogen atom; nucleotide hydrogen atom; uracil hydrogen atom; ESR nucleic acid constituent; radical nucleic acid constituent.
The reaction of H· atoms produced in acidic glasses (H2SO4 and H3PO4) by radiolysis and photolysis with the nucleic acid constituents by uracil, thymine, and the row of 5-halo-substituted uracils as well as their nucleoside (nucleotide) derivatives and deoxyribose were studied by ESR spectroscopy. With the pyrimidines, addition at either site of the 5,6 double bond was the only reaction, the relative yield of 5-yl or 6-yl radicals depending largely on the nature of the nonhydrogen 5 or 6 substituent. The spectral parameters of both radical types were determined by spectra simulation. In deoxyribose, abstraction of a carbon-bound hydrogen takes place from probably only 2 initial sites, the corresponding radicals undergoing a fast and a slow secondary reaction. In nucleosides (nucleotides), the base and deoxyribose (deoxyribose phosphate) moiety react independently. The relative yield of both subgroup radicals was determined and explained in terms of a “”miss or react”” mechanism. The findings are discussed in terms of solid-state vs. liquid solution type reaction mechanisms.
Journal of Physical Chemistry published new progress about ESR (electron spin resonance). 4956-05-2 belongs to class pyrimidines, and the molecular formula is C3H2BrN3O2, Electric Literature of 4956-05-2.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia