S., Gunasekar et al. published their research in Materials Today: Proceedings in 2021 | CAS: 90905-32-1

2-Methoxypyrimidine-5-carbaldehyde (cas: 90905-32-1) belongs to pyrimidine derivatives. Heterocyclic compounds bearing the pyrimidine core are of tremendous interest as they constitute an important class of natural and synthetic compounds exhibiting diverse useful biological activities that hold attractive potential for clinical translation as therapeutic agents in alleviation of a myriad of diseases. For example, the neurotoxin tetrodotoxin is a pyrimidine derivative. It is found in a number of species including the Japanese puffer fish, the blue-ringed octopus, and the orange-bellied newt. Tetrodotoxin prevents the transmission of nerve signals and can result in paralysis and death.Application In Synthesis of 2-Methoxypyrimidine-5-carbaldehyde

Synthesis and biological evaluations of new pyrazole hydrazides as potent anti-microbial agent was written by S., Gunasekar;M., Saamanthi;S., Aruna. And the article was included in Materials Today: Proceedings in 2021.Application In Synthesis of 2-Methoxypyrimidine-5-carbaldehyde This article mentions the following:

A sequence of pyrazole hydrazides I (R = 4-methoxy-2,3-dimethylphenyl, 6-chloropyridin-3-yl, 2-methoxypyrimidin-5-yl, 4-(benzyloxy)benzen-1-yl, etc.) was synthesized I (R = 4-methoxy-2,3-dimethylphenyl), and its anti-microbial activities were studied for its in vitro anti-microbial activities against staphylococcus aureus and Escherichia coli and found almost all synthesized mols. I are active. Also synthesized mols. were ascertained by 1H NMR, 13C NMR and mass spectroscopy and pyrazole hydrazide I was synthesized by dehydration reaction of N-(5-[(hydrazinecarbonyl)methyl]-1H-pyrazol-3-yl)-4-(trifluoromethyl)benzamide with different aldehydes RCHO. All the reaction progress were monitored by TLC. Min. inhibition values of synthesized mols. were studied using Staphylococcus aureus and Escherichia coli and some of the compounds show good MIC values such as I (R = 2,3-dichlorophenyl (24), 6-chloropyridin-3-yl (23), 2-methoxypyrimidin-5-yl (23)) as compared to existing drug cefotaxime. In the experiment, the researchers used many compounds, for example, 2-Methoxypyrimidine-5-carbaldehyde (cas: 90905-32-1Application In Synthesis of 2-Methoxypyrimidine-5-carbaldehyde).

2-Methoxypyrimidine-5-carbaldehyde (cas: 90905-32-1) belongs to pyrimidine derivatives. Heterocyclic compounds bearing the pyrimidine core are of tremendous interest as they constitute an important class of natural and synthetic compounds exhibiting diverse useful biological activities that hold attractive potential for clinical translation as therapeutic agents in alleviation of a myriad of diseases. For example, the neurotoxin tetrodotoxin is a pyrimidine derivative. It is found in a number of species including the Japanese puffer fish, the blue-ringed octopus, and the orange-bellied newt. Tetrodotoxin prevents the transmission of nerve signals and can result in paralysis and death.Application In Synthesis of 2-Methoxypyrimidine-5-carbaldehyde

Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia