Sandosham, Jessie published the artcileSyntheses of 5-alkenylpyrimidines by organotin reactions, HPLC of Formula: 84755-30-6, the main research area is stannylpyrimidine preparation coupling alkenyl bromide; vinylpyrimidine; alkenylpyrimidine; halopyrimidine coupling vinyltin; pyrimidine alkenyl.
5-Stannylpyrimidine I (R = SnBu3) (II) was prepared from I (R = Br) by lithiation at -95° and quenching with Bu3SnCl. II is used in Pd-catalyzed coupling reactions with vinyl bromides to give 5-vinylpyrimidines I (R = CH:CHR1, R1 = H, Me, Ph). The opposite reaction sequence, i.e. Pd-catalyzed coupling between 5-halopyrimidines and vinyltin derivatives, is also described. Alternatively, the 5-vinylpyrimidines have been obtained by dehydrohalogenation with CsF and by a modified Wittig reaction. 2-Methylthiopyrimidines are transformed into the 2-methoxy derivatives or 2-pyrimidinones using chloramine-T in a simple one-pot synthesis.
Acta Chemica Scandinavica, Series B: Organic Chemistry and Biochemistry published new progress about Coupling reaction. 84755-30-6 belongs to class pyrimidines, name is 4-Methyl-2-(methylthio)pyrimidine-5-carbaldehyde, and the molecular formula is C7H8N2OS, HPLC of Formula: 84755-30-6.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia