Sandosham, Jessie; Undheim, Kjell published the artcile< Stannylation in the electrophilic 2- and 4/6-pyrimidine position and the use of stannylpyrimidines in coupling and tin-lithium exchange reactions>, Quality Control of 3921-01-5, the main research area is stannylation electrophilic pyrimidine lithio; stannylpyrimidine coupling acyl chloride bromide; tin lithium exchange reaction stannylpyrimidine; carbonyl compound coupling stannylpyrimidine.
2-Stannylpyrimidines have been prepared by stannyl anion substitution in 2-chloropyrimidines. Stannylation in the 4-position was via the iodo-derivative or via the 4-lithio derivative and lithium-tin transmetalation. Tin-lithium exchange in the 2-position resulted in 2-lithiopyrimidine. Ketones were formed from the stannylpyrimidines and acid chlorides, aryl bromides required Pd-catalysis for coupling reaction.
Tetrahedron published new progress about Acid chlorides Role: RCT (Reactant), RACT (Reactant or Reagent). 3921-01-5 belongs to class pyrimidines, and the molecular formula is C4H2Br2N2, Quality Control of 3921-01-5.
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia