Adding a certain compound to certain chemical reactions, such as: 89793-12-4, Ethyl 2-chloropyrimidine-5-carboxylate, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Recommanded Product: 89793-12-4, blongs to pyrimidines compound. Recommanded Product: 89793-12-4
To a 250 mL single-necked flask equipped with magnetic stirring was added 1,4-dioxane (100 mL) and Compound 1 (10.0 g, 53.59 mmol).Stirring was dissolved, cooled in an ice water bath, and then compound 2 (9.98 g, 53.59 mmol) was added.DIPEA (20.8 mL, 134 mmol) was removed, and the ice bath was removed, and the mixture was stirred at room temperature for 3 hours under a nitrogen atmosphere.The solvent was distilled off under reduced pressure, and silica gel column to give 18.0 g of a white solid, a yield of 99.85%.
The synthetic route of 89793-12-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Shenzhen Tajirui Bio-pharmaceutical Co., Ltd.; Wang Yihan; Li Huanyin; (47 pag.)CN109970745; (2019); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia