Share a compound : 4,6-Diphenylpyrimidin-2-amine

According to the analysis of related databases, 40230-24-8, the application of this compound in the production field has become more and more popular.

Reference of 40230-24-8, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 40230-24-8, name is 4,6-Diphenylpyrimidin-2-amine. This compound has unique chemical properties. The synthetic route is as follows.

98.9 g (0.4 mol) of 2-amino-4,6-diphenyl-1,3-pyrimidine (compound 1) are introduced into a solution consisting of 1.5 l of water and 1 l of concentrated sulfuric acid. A solution of 75.0 g (1.088 mol) of sodium nitrite in 500 ml of water is added dropwise below the surface of the yellow suspension over the course of 25 hours. After 20 hours at 20-25 C. the yellow suspension is poured into 15 l of water and is rendered alkaline using 2.25 l of 25% aq. ammonia. The product precipitates as a beige solid. It is filtered off, washed with water and dried in a vacuum oven. 88.3 g (=88.9% yield) of beige crystals are obtained of the formula [C00057] [00399] with a melting point of 234-236 C.

According to the analysis of related databases, 40230-24-8, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Ciba Specialty Chemicals Corporation; US6706215; (2004); B1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia