Adding a certain compound to certain chemical reactions, such as: 573675-29-3, 7-Bromopyrido[3,2-d]pyrimidin-4(3H)-one, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, HPLC of Formula: C7H4BrN3O, blongs to pyrimidines compound. HPLC of Formula: C7H4BrN3O
4. Bromo-4-chloropyrido 3-2-dJpyrirnidiyze Heat a mixture of 7-bromopyrido [3, 2-d] pyrimidin-4-ol (35 mg, 0.15 mmol) and POCL3 (10 mL) at 90C for 16 hours. Evaporate the POC13, and add ice (100 g) followed by careful addition of saturated NaHCO3. Extract twice with EtOAc, dry (Na2S04), and evaporate to provide bromo-4-chloropyrido [3-2-d] pyrimidine as a white solid.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,573675-29-3, 7-Bromopyrido[3,2-d]pyrimidin-4(3H)-one, and friends who are interested can also refer to it.
Reference:
Patent; NEUROGEN CORPORATION; WO2005/42498; (2005); A2;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia