Electric Literature of 30129-57-8, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 30129-57-8, name is 6-Methyl-1H-pyrazolo[3,4-d]pyrimidin-4(7H)-one. This compound has unique chemical properties. The synthetic route is as follows.
3-Iodo-6-methyl-1 ,5-dihydro-4H-pyrazolo[3,4-dJpyrimidin-4-one. To a stirred20 suspension of 6-methyl-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one (80.0 g, 533 mmol) in dimethylacetamide (800 mL) was added N-iodosuccinimide (180 g, 799 mmol) portion-wise over aperiod of 30 min. The reaction mixture vas heated to 130C for 3 hours. The reaction mixturewas cooled to 0C and poured into a saturated aqueous solution ofNa2S203 (1.8 L) with stining.The mixture was allowed to settle for 3 h and the precipitated brown solid was filtered. The25 isolated brown solid was suspended in THF:Cf:bCN:MeOH:FhO (3:3:2:3) and stirred for 16 h.The resulting solid was filtered and dried under vacuum to provide the title compound (60 g,41 ~o) as a brown solid. 1H NNIR (400 NIHz, DMSO-do) 8 13.02 (s, 1H), 12.04 (s, 1H), 2.32 (s,3H). [M+H] ‘” 276.9.
According to the analysis of related databases, 30129-57-8, the application of this compound in the production field has become more and more popular.
Reference:
Patent; DART NEUROSCIENCE, LLC; GOMEZ, Laurent; VERNIER, William, Francois; (104 pag.)WO2018/125810; (2018); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia