Application of 10070-92-5, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 10070-92-5, name is Pyrimidine-5-carbaldehyde, molecular formula is C5H4N2O, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
Pyrimidine-5-formaldehyde (1.00 g, 9.25 mmol),2,4-Dimethylphenylhydrazine hydrochloride (1.60 g, 9.30 mmol)And DMF (16 mL) was added to a 100 mL single-neck round bottom flask in turn.Reaction at room temperature for 1 h,Neutralize the hydrochloride with 8 mL of saturated sodium bicarbonate solution, then add water (80 mL).A yellow solid precipitated, and the solid was filtered, washed with water (50 mL¡Á2).Dissolve in dichloromethane (20 mL), separate the layers, and collect the organic phase.The title compound was obtained as a yellow solid (1.20 g, 57.0%).
According to the analysis of related databases, 10070-92-5, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Guangdong Dongyangguang Pharmaceutical Co., Ltd.; Chen Kangzhi; Jin Chuanfei; Luo Ming; Zhang Yingjun; (28 pag.)CN108863948; (2018); A;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia