Sharif, Ehesan U.’s team published research in Organic Process Research & Development in 24 | CAS: 56-05-3

Organic Process Research & Development published new progress about 56-05-3. 56-05-3 belongs to pyrimidines, auxiliary class Pyrimidine,Chloride,Amine,API, name is 2-Amino-4,6-dichloropyrimidine, and the molecular formula is C9H21NO3, Synthetic Route of 56-05-3.

Sharif, Ehesan U. published the artcileDevelopment of a Scalable and Practical Synthesis of AB928, a Dual A2a/A2b Receptor Antagonist, Synthetic Route of 56-05-3, the publication is Organic Process Research & Development (2020), 24(7), 1254-1261, database is CAplus.

First- and second-generation routes to the dual A2a/A2b receptor antagonist AB928 I are disclosed. The second-generation route (performed on multigram scale) prepared the aminochloropyridinylbenzonitrile II by a route avoiding palladium-catalyzed borylation and Suzuki coupling reactions required in the initial route which generated significant amounts of byproducts.

Organic Process Research & Development published new progress about 56-05-3. 56-05-3 belongs to pyrimidines, auxiliary class Pyrimidine,Chloride,Amine,API, name is 2-Amino-4,6-dichloropyrimidine, and the molecular formula is C9H21NO3, Synthetic Route of 56-05-3.

Referemce:
https://pubchem.ncbi.nlm.nih.gov/compound/Pyrimidine,
Pyrimidine – Wikipedia