(2,3-Dibromopropyl)sulfonylarenes in S,N-Tandem Heterocyclizations. A New Synthesis of Thiazolopyrimidines was written by Shklyarenko, A. A.;Chernitsa, B. V.;Yakovlev, V. V.. And the article was included in Russian Journal of Organic Chemistry in 2005.HPLC of Formula: 39083-15-3 The following contents are mentioned in the article:
A new method for the synthesis of dihydrothiazolo[3,2-a]pyrimidinones, e.g. I, via S,N-tandem heterocyclization/alkylation of aryl 2,3-dibromopropyl sulfones and 2-thiouracils, is reported. The absence of isomeric products in the reaction mixtures indicates high chemo- and regioselectivity of this tandem reaction and suggests a concerted mechanism. This study involved multiple reactions and reactants, such as 5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3HPLC of Formula: 39083-15-3).
5-Ethyl-6-methyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one (cas: 39083-15-3) belongs to pyrimidine derivatives. Pyrimidine also found in many synthetic compounds such as barbiturates and the HIV drug, zidovudine. As nucleotides in DNA and RNA, pyrimidine nucleotide derivatives have a wide range of biological applications. For example, pyrimidine derivatives are useful in DNA repair studies involving cancer and epigenetics.HPLC of Formula: 39083-15-3
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia