On July 1, 2015, Shore, Daniel G. M.; Wasik, Kimberly A.; Lyssikatos, Joseph P.; Estrada, Anthony A. published an article.COA of Formula: C5HCl2F3N2 The title of the article was Minisci alkylations of electron-deficient pyrimidines with alkyl carboxylic acids. And the article contained the following:
A practical method for the Minisci reaction of electron-deficient pyrimidines with carboxylic acids is described. The one-step protocol allows for the alkylation of halo- and trifluoromethyl pyrimidines with a variety of readily available alkyl and (hetero)cycloalkyl carboxylic acids. These conditions permitted the facile synthesis of substituted pyrimidines, which are poised for further elaboration through divergent means. The experimental process involved the reaction of 2,5-Dichloro-4-(trifluoromethyl)pyrimidine(cas: 785777-98-2).COA of Formula: C5HCl2F3N2
The Article related to minisci alkylation electron deficient pyrimidine alkyl carboxylic acid, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.COA of Formula: C5HCl2F3N2
Referemce:
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia