Related Products of 1558-17-4 ,Some common heterocyclic compound, 1558-17-4, molecular formula is C6H8N2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
To 10 mL of an aqueous 5N sodium hydroxide solution were added 0.21 g (2.0 mmol) of 4,6-dimethylpyrimidine, 1.1 g (4 mmol) of 4-methoxy-3-(4-methoxybenzyloxy)benzaldehyde, and 0.1 g (0.29 mmol) of tetrabutylammonium hydrogen sulfate, followed by heating under ref lux. The precipitate thus formed was filtered and washed with water. Then, it was dried in a vacuum drier and recrystallized in ethylacetate to afford 1.06 g of (E,E)-4,6-bis[4′-methoxy-3′-(4-methoxybenzyloxy)styryl]pyrimidine.1H NMR (DMSOd6, 400 MHz) delta 3.81 (s, 6H), 3.91 (s, 6H), 5.12 (s, 4H), 6.87 (d, J=15.9 Hz, 2H), 6.91 (d, J=8.6 Hz, 2H), 6.92 (d, J=8.5 Hz, 4H), 7.18 (d, J=8.6 Hz, 2H), 7.19 (s, 2H), 7.22 (s, 1H), 7.40 (d, J=8.5 Hz, 4H), 7.78 (d, J=15.9 Hz, 2H), 9.03 (s, 1H)
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 1558-17-4, 4,6-Dimethylpyrimidine, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY; US2010/190803; (2010); A1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia