Simple exploration of 2-Bromo-4-methylpyrimidine

According to the analysis of related databases, 130645-48-6, the application of this compound in the production field has become more and more popular.

Related Products of 130645-48-6, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 130645-48-6, name is 2-Bromo-4-methylpyrimidine. This compound has unique chemical properties. The synthetic route is as follows.

PREPARATION EXAMPLE 54 Synthesis of 4-methyl-2-(3,4,5-Trimethoxyphenyl)-pyrimidine 2-Bromo-4-methylpyrimidine (1.5 g) and 3,4,5-trimethoxyphenylboronic acid (1.83 g) were reacted in the same manner as in Preparation Example 1 to obtain the title compound. Yield: 1.49 g (67%). 1H-NMR (400 MHz, CDCl3) delta: 2.57 (s, 3H), 3.92 (s, 3H), 3.99 (s, 6H), 7.01 (d, 1H, J=5.1 Hz), 7.77 (s, 2H), 8.61 (d, 1H, J=5.1 Hz).

According to the analysis of related databases, 130645-48-6, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Kowa Co., Ltd.; US6509329; (2003); B1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia