Simple exploration of 2,4-Dichloro-5,6-dimethylpyrimidine

At the same time, in my other blogs, there are other synthetic methods of this type of compound,1780-32-1, 2,4-Dichloro-5,6-dimethylpyrimidine, and friends who are interested can also refer to it.

With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.1780-32-1, name is 2,4-Dichloro-5,6-dimethylpyrimidine, molecular formula is C6H6Cl2N2, molecular weight is 177.03, as common compound, the synthetic route is as follows.Formula: C6H6Cl2N2

After 1-methoxymethyl-1,2,3,4-tetrahydroisoquinolin(0.5 g, 2.82 mmol) and triethylamine(0.4 ml, 2.82 mmol) were added to a suspension of 5,6-dimethyl-2,4-dichloropyrimnidine(0.48 g, 2.68 mmol) in dimethylformamide (5 ml), 0.5 g of the titled compound was obtained in accordance with the same procedure as in Step 1 of Example 35.

At the same time, in my other blogs, there are other synthetic methods of this type of compound,1780-32-1, 2,4-Dichloro-5,6-dimethylpyrimidine, and friends who are interested can also refer to it.

Reference:
Patent; Yuhan Corporation; US6352993; (2002); B1;,
Pyrimidine | C4H4N2 – PubChem,
Pyrimidine – Wikipedia